To analyze the diagnostic value of the cerebroplacental ratio (CPR) and the umbilical artery blood flow detected by Doppler ultrasound of pregnant women for their fetal growth restriction (FGR). Methods: 90 pregnant women with FGR diagnosed by antenatal examination in hospital were selected in observation group, and 80 normal pregnant women were selected in control group between July 2022 and July 2023. The values of umbilical artery pulsatilityindex (PI), resistance index (RI), maximum systolic blood flow velocity to end-diastolic blood flow velocity (S/D) ratio and CPR of the women in the two groups were detected by Doppler ultrasound. The adverse pregnancy outcomes of the women in the two groups were counted. The values of PI, RI, S/D and CPR, and the incidence of adverse pregnancy outcomes of the women were compared between the two groups. Receiver operator characteristic (ROC) curve was used to evaluate the predictive value of the values of PI, RI, S/D and CPR of the women for their FGR. Results: The PI, RI, S/D and CPR values of the women in the two groups had decreased with the increase of their gestational weeks. The values of PI, RI and S/D of the women in the observation group during 32-33+6 gestational weeks, 34-36+6 gestational weeks and 37-40 gestational weeks were significantly higher than those of the women in the control group, and the CPR value of the women in the observation group was significantly lower (P<0.05). ROC curve analysis showed that the area under the curve of the combination of the values of PI, RI, S/D and CPR of the women for diagnosing their FGR during 37-40 gestational weeks was 0.957, and the sensitivity of which was 97.5%, and both of which were significantly higher than those of the PI value, the RI value, the S/D value or the CPR value alone (P<0.05). The rates of the neonatal asphyxia and low birth weight, and the neonatal Apgar score in the observation group were significantly lower than those in the control group (P<0.05). Conclusion: The CPR combined with umbilical artery blood flow parameters values of the pregnant women for diagnosing their FGR can increase the diagnostic efficacy and the diagnostic sensitivity.