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Comparison of effect of cervical cerclage and progesterone for treating singleton pregnant women with short cervix(<10 mm) |
1. The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, 210029;2. Huai 'an Maternal and Child Health Care Hospital |
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Abstract To compare and analyze the effect of cervical cerclage and progesterone for treating singleton pregnant women with short cervix(<10 mm). Methods: 132 singleton pregnant women with short cervix(<10 mm) between June 2018 and June 2021 were collected retrospectively. These women were divided into group A(83 cervical cerclage treatment) and group B(49 women with progesterone treatment) according to different treatment methods. The cumulative delivery rate, the pregnancy status, the neonatal status, and the incidence of complications of the women were compared between the two groups. Results: There was no significant difference in the delivery mode of the women between the two groups(P>0.05). The cumulative delivery rate(81.9%) of the women during ≥37 gestational weeks in group A was significantly higher than that(63.3%) of the women in group B, the gestational weeks at delivery(36.6±2.1 weeks) and the gestational prolongation time(20.4±3.7 weeks) of the women in group A were significantly longer than those(35.6±2.3 weeks and 19.1±3.8 weeks) of the women in group B(all P<0.05). There was no significant difference in the neonatal survival rate between the two groups(P>0.05). The birth weight of neonates(2.8±0.4kg) in group A was significantly higher than that(2.5±0.4kg)in group B, the proportion of the neonates transferred in neonatal department(15.7%) in group A was significantly lower than that(34.7%) of the neonates in group B, and the neonatal Apgar score(8.0±1.4 points) in group A was significantly higher than that(7.5±1.2 points) in group B (P<0.05). There was no significant difference in the complication rate(10.2% vs.12.1%) of the women between the two groups(P>0.05). Conclusion: The effect of cervical cerclage for treating singleton pregnant women with short cervix<10 mm is higher than that of progesterone treatment. The rational use of drugs for anti-infection and control uterine contraction, and regular monitoring vaginal secretions situation of these pregnant women can reduce their rate of infection after cerclage and can decrease their incidence of premature delivery.
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