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Research progress of the application of vaginal ring in female reproductive health |
1.National Research Institute for Family Planning, Beijing, 100081; 2.Graduate School of Peking Union Medical College |
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Abstract In recent years, the problem of female reproductive health has become increasingly prominent. How to achieve better treatment effect of female diseases is a hot issue to be solved urgently. Vaginal ring is a ring made of elastomers drug delivery system, which can avoid the oral preparation of the first pass effect and can achieve long-term sustained drug release effect. Vaginal ring can improve drug absorption rate and reduce drug side effects in the form of partial dosing vaginal mucosa absorption, and which can increase the female compliance and do not require operation by professional providers. Vaginal ring as a new drug delivery system has been used in contraception, hormone replacement therapy, assisted reproduction, antitumor, and antivirus, etc. This paper aims to introduce the vaginal ring structure and to summarize the research progress of the application of vaginal ring in reproductive health based on different disease, so as to provide new ideas of drug therapy for the female reproductive disease.
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