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| Diagnostic value of transvaginal color Doppler ultrasound combined with serumβ-human chorionic gonadotropin level for uterine incision pregnancy |
| 1. The First People's Hospital of Anqing, Anhui Province, 246000; 2.Anqing Medical College |
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Abstract To investigate the value of transvaginal color Doppler ultrasound combined with serum β-human chorionic gonadotropin (β-HCG) level of women for diagnosing their uterine incision pregnancy. Methods: From February 2018 to November 2021, 90 women with suspected uterine incision pregnancy were selected as the research objects, which included 46 cases with normal pregnancy in group A and 44 cases with uterine incision pregnancy in group B after confirmed by surgical pathology. Enzyme linked immunosorbent assay (ELISA) was used to detect the level of serum β-HCG of these women, and the sac situation of these women was examinated by transvaginal color Doppler ultrasound. The consistency of results of transvaginal color Doppler ultrasound or serum β-HCG level, and clinical pathological for diagnosing uterine incision pregnancy was analyzed. And the values of transvaginal color Doppler ultrasound, the serum β-HCG level, and the examination of ultrasound combined with serum β-HCG level for diagnosing uterine incision pregnancy were also analyzed. Results: The level of serum β-HCG (1768.24±421.74 U/L) of the patients in group B was significantly higher than that (1020.83±302.44 U/L) of the patients in group A (P<0.05). Transvaginal color Doppler ultrasound and serum β-HCG level confirmed uterine incision pregnancy in 37 cases and 34 cases, respectively, which had high consistency with the clinicopathological diagnosis of uterine incision pregnancy (Kappa=0.710, 0.598, all P<0.05). 41 cases with uterine incision pregnancy were confirmed by the combination of transvaginal color Doppler ultrasound and the serum β-HCG level, which had excellent consistency with the clinicopathological diagnosis (Kappa=0.889, P<0.05). The sensitivity (90.9%), the accuracy (94.4%), and the negative predictive value (91.8%) of the combination of transvaginal color Doppler ultrasound and the serum β-HCG level for diagnosing uterine incision pregnancy were significantly higher than those of the serum β-HCG level or ultrasound alone, and the missed diagnosis rate (2.2%) of the combination of transvaginal color Doppler ultrasound and serum β-HCG level for diagnosing uterine incision pregnancy was significantly lower than that of the serum β-HCG level or ultrasound alone (all P<0.05). Conclusion: Transvaginal Color Doppler ultrasound combined with serum β-HCG level for diagnosing uterine incision pregnancy can effectively increase the diagnostic rate, and decrease the missed diagnosis rate.
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