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| Effects of acupuncture combined with clomid for treating women with polycystic ovary syndrome |
| 1.Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437; 2.Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine |
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Abstract To explore the effects of acupuncture combined with clomid for treating women with polycystic ovary syndrome (PCOS) on their pregnancy outcomes. Methods: A total of 120 women with PCOS of liver depression transforming fire and spleen deficiency and phlegm-dampness type were enrolled in this study and were divided into two groups by simple randomized grouping mode between June 2018 and December 2020. The women in the observation group were given acupuncture combined with oral clomiphene tablets, and the women in the control group were given oral clomiphene tablets. After 3 months of continuous treatment, the clinical curative effect, the development situations of follicle and endometrium, the ovulation, and the pregnancy of the women were compared between the two groups. The occurrence of adverse reactions of the women in both groups was recorded. Results: After treatment, the total effective rate (93.3%) of the women in the observation group was significantly higher than that (80.0%) of the women in the control group, the diameter of mature follicle (26.7±5.0mm) of the women in the observation group was significantly longer than that (21.5±4.6mm) of the women in the control group, and the endometrial thickness (8.3±1.2mm) of the women in the observation group was significantly more than that (7.4±1.2mm) of the women in the control group. The type A rate of endometrial morphology (60.0%) of the women in the observation group was significantly higher than that (41.7%) of the women in the control group, and the rates of ovulation (86.7%) and clinical pregnancy (51.7%) of the women in the observation group were significantly higher than those (66.7% and 31.7%) of the women in the control group. The incidences of unruptured follicular luteinization syndrome (1.7%) and the ovarian hyperstimulation syndrome (3.3%) of the women in the observation group were significantly lower than those (15.0% and 16.7%) of the women in the control group (all P<0.05), and the incidence of adverse reactions (3.3%) of the women in the observation group had no significant different from that (1.7%) of the women in the control group (P>0.05). Conclusion: Acupuncture combined with clomid for treating women with PCOS has better clinical efficacy, which is more conducive to improving the pregnancy outcomes of these women.
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