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| The levels of fibrinogen, D-dimer, and platelet in venous blood of pregnant women with threatened abortion during early pregnancy and their clinical significance |
| Qingdao Jiaozhou Central Hospital, Qingdao, Shandong Province, 266300 |
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Abstract To explore the levels of fibrinogen (Fg), D-dimer (D-D), and platelet (PLT) in venous blood of pregnant women with threatened abortion during early pregnancy, and to study their clinical significance. Methods: 60 pregnant women with threatened abortion were selected in study group and 59 normal pregnant women were selected in control group from January 2018 to January 2020. Venous blood samples of these women were collected to detect their Fg, DD, and PLT levels. The levels of Fg, DD, and PLT of the women were compared between the two groups, and which were also compared among the women with different abortion history and among the women with different pregnancy outcomes in the study group. Results: The levels of DD, Fg, and PLT of the women in the study group were significantly higher than those of the women in the control group (P＜0.05). There were significantly different in D-D level of the women in the study group among the women with natural delivery, the women with inevitable abortion, and the women with missed abortion (P＜0.05). The levels of DD, Fg, and PLT of the women with abortions less than twice were significantly lower than the women with twice or more abortions (P＜0.05). Conclusion: The D-D, Fg, and PLT levels in venous blood of the pregnant women with threatened abortion during the first trimester of pregnancy are abnormal increasing, and which increase with the increase of the abortion times, so it suggests that the D-D, Fg, and PLT levels may be used to judge threatened abortion during early pregnancy and the adverse outcomes of the pregnant women.
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