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Abstract To investigate the value of thrombelastography (TEG) and indexes of blood coagulation function for diagnosing gestational hypertension (GH) and for evaluating pregnancy outcomes of pregnant women. Methods: 150 pregnant women with GH were included in group A and 80 normal pregnant women were selected in group B from January 2018 to August 2020. According to the severity of GH, the women in group A were divided into group A1 (women with simple GH), group A2 (women with mild preeclampsia), and group A3 (women with severe preeclampsia). According to the pregnancy outcomes, the women in group A were further divided in group A4 (women with adverse pregnancy outcomes) and group A5 (women without adverse pregnancy outcomes). The differences of TEG and coagulation indexes of the women were compared among these groups and between the women before and after treatment. Results: The R value of the women in group B, group A1, group A2, and group A3 had decreased gradually, while their MA and CI values had increased gradually (P＜0.05). The K value of the women in group A3 was the lowest, and the value of α Angle of the women in group A3 was the highest, and the α Angle value of the women in group A1 and group A2 was significantly higher than that of the women in group B (P＜0.05). The PT value of the women in group B, group A1, group A2, and group A3 had decreased gradually, while their D-D value had increased gradually (P＜0.05). The values of APTT and TT of the women in group A3 were the lowest, while their FIB value of the women in group A3 was the highest (P＜0.05). There were significant differences in the values of R, α Angle, MA, CI, and PT of the women in group A1 between before and after treatment (P＜0.05), but there were no significant differences in the values of K, APTT, TT, FIB, and D-D of the women in group A1 between before and after treatment (P＞0.05). There were significant differences in the values of R, K,α Angle, MA, CI, PT, APTT, TT, and D-D of the women in group A2 between before and after treatment (P＜0.05), but there was no significant difference in the FIB value of the women in group A2 between before and after treatment (P＞0.05). There were significant differences in age, body mass index, type of GH, the values of R, MA, CI, and PT, and D-D of the women between group A4 and group A5 (P＜0.05), but there were no significant differences in the values of K, α Angle, APTT, TT, and FIB of the women between group A4 and group A5 (P＞0.05). Age, mild preeclampsia, severe preeclampsia, R<3min, MA>70mm, D-D≥0.5μg/mL of the pregnant women with GH were the independent risk factors of their adverse pregnancy outcomes (OR>1, P＜0.05). Conclusion: Both the values of TEG and blood coagulation indexes can evaluate the type of GH, the therapeutic effect, and the pregnancy outcomes of the pregnant women with GH, and the TEG value has better evaluation ability.
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