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Effects of laparoscopic and hysteroscopic surgery for treating patients with type Ⅱ of submucosal uterine fibroids on their cervical local microcirculation and serum AMH level |
1.Beijing Longfu Hospital, Beijing,1000; 2.Beijing Hospital |
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Abstract To explore the curative effect of laparoscopic and hysteroscopic surgery for treating patients with type Ⅱ of submucosal uterine fibroids, and to study their influence on the cervical local microcirculation and the serum anti-Mullerian hormone (AMH) level of the patients. Methods: The clinical data of 112 patients with type Ⅱ of submucosal uterine fibroids from June 2018 to June 2019 were analyzed retrospectively. These patients were divided into group A (56 patients with laparoscopic surgery) and group B (56 patients with hysteroscopy surgery) according to different surgical procedures. The operation-related indicators, and the situations of postoperative complications, pregnancy, and recurrence of the patients were compared between the two groups. The cervical local microcirculation parameters and the serum levels of AMH, follicle stimulating hormone (FSH), estradiol (E2) of the patients before and after surgery were measured. Results: The operative time, intraoperative blood loss, postoperative anal exhaust time, and hospital stay time of the patients in group B were significantly lower than those of the patients in group A, and the rate of one-time resection of myoma (100.0%) of the patients in group A was significantly higher than that (91.1%) of the patients in group B (all P<0.05). There were no significant changes in the cervical capillary diameter and the blood perfusion volume, and the serum AMH, FSH, and E2 levels of the patients between the two groups and between before and after operation (P>0.05). There were no significant differences in the incidences of complications (14.3% vs. 7.1%), the recurrence rate of uterine fibroids (10.7% vs. 3.6%), and the pregnancy rate after operation (76.7% vs. 68.1%) of the patients between the two groups (all P>0.05). The duration of post operation to pregnancy of the patients in group B was significant shorter than that of the patients in group A (P<0.05). Conclusion: Laparoscopic and hysteroscopic surgery for treating the patients with type Ⅱ of submucosal uterine fibroids have significant effect with less influence on the local cervical microcirculation and the AMH level of the patients. Laparoscopic surgery has higher rate of resection at once, but hysteroscopic surgery has advantage of less trauma and less blood loss during operation, which is more conducive to shorten the duration of post operation to pregnancy.
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