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| Autophagy of placenta and preeclampsia |
| 1.The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin，Heilongjiang Province,150040；2.Heilongjiang University of Traditional Chinese Medicine |
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Abstract Preeclampsia (PE) is a pregnancy-specific and multisystem disorder of the pregnant women. Due to the complexity of the pathological mechanism, the treatment of PE is still based on the main principles of alleviating clinical symptoms and timely delivery at present. PE is considered a placental-derived disease，and the homeostasis of the placenta is regulated by autophagy. However, there are still different views in the role of placental autophagy in the pathogenesis of PE, which needs to be further clarified. Based on the new findings, this paper reviews the role of several factors related to placental autophagy in PE pathology, in order to provide useful clues for the prevention and treatment of PE.
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