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Value of the fetal hemodynamic parameters of fetal middle cerebral artery, umbilical artery, and umbilical ductus venosus that examined by color Doppler ultrasound for predicting fetal intrauterine hypoxia |
The Fourth People's Hospital of Shanxi Province, Xi'an Shanxi Province, 710043 |
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Abstract To explore the value of hemodynamic parameters of fetal middle cerebral artery(MCA), umbilical artery(UA), and umbilical ductus venosus(DV) that examined by color Doppler ultrasound for diagnosing fetal intrauterine hypoxia. Methods: From January 2019 to August 2020, 85 pregnant women with fetal intrauterine hypoxia during the third trimester of pregnancy(36-41+6 gestational weeks) were selected in study group, and another 150 pregnant women without fetal intrauterine hypoxia during the third trimester of pregnancy were selected in control group. Color Doppler ultrasound examination of the women in the two groups was performed at admission. The resistance index(RI), pulsatility index(PI), and systolic flow velocity peak / diastolic flow velocity end(S/D) of MCA and UA of the women were detected. The values of fetal MCA and UAM parameters, such as RI, PI, and S/D, in the two groups were calculated, and the values of fetal umbilical venous blood flow(QUV) and DV blood flow(QDV) in the two groups were measured. The fetal DV shunt rate in the two groups was calculated, and the differences of the above fetal parameters were compared between the two groups. The receiver operating characteristic curve(ROC curve) was drawn to explore the predictive value of RI, PI, S/D of MCA and UA, and DV shunt rate for fetal intrauterine hypoxia. Results: The values of RI, PI, and S/D values of fetal MCA in the study group were significant lower than those in the control group, but the values of RI, PI, and S/D of fetal MCA in the study group were significant higher than those in the control group. The values of RI, PI and S/D of fetal MCA/UA in the study group were significantly lower than those in the control group(all P<0.05). There was no significant difference in fetal QDV value between the two groups(P>0.05), but fetal QUV value in the study group was significantly lower than that in the control group, DV shunt rate in the study group was significant higher(P<0.05). The areas under ROC curve of the RI value, PI value, and S/D value of MCA/UA, and the DV value, and the combined values of RI, PI, S/D of MCA/UA, and DV for diagnosing fetal intrauterine hypoxia were 0.784, 0.802, 0.830, 0.835, 0.967, respectively(P<0.05). Conclusion: Early fetal intrauterine hypoxia has the changes of the hemodynamic parameters, such as MCA, UA, and DV. Combined examination of RI, PI, and S/D of MCA and UA, and DV shunt rate by ultrasound has higher value for predicting fetal intrauterine hypoxia.
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