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Clinical curative effect analysis of ferrous eumanate and docusate sadium capsule combined with Jianpi shengxue granule or polysaccharide-iron complex for treating pregnant women with iron deficiency anemia |
Henan Provincial People's Hospital, Zhengzhou, Henan Province, 450000 |
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Abstract To explore the clinical curative effect of ferrous eumanate and docusate sadium capsule combined with Jianpi shengxue granule for treating pregnant women with iron deficiency anemia(IDA). Methods: A total of 120 pregnant women with IDA were prospectively selected and randomly divided into three groups(50 cases in each group) by random number table. The women in group A were given polysaccharide-iron complex, the women in group B were given polysaccharide-iron complex and ferrous eumanate and docusate sadium capsule, and the women in group C were given polysaccharide-iron complex, ferrous eumanate and docusate sadium capsule, and Jianpi shengxue granule. The women in the three groups were treated for 4 weeks. The clinical efficacy of the women was compared among the three groups. Results: The total effective rate of the women in group B(88.0%) or group C(96.0%) was significantly higher than that(82.0%) of the women in group A(P<0.05). After treatment, there were no significant differences in the values of red blood cell, hemoglobin, and mean corpuscular volume, and the levels of serum iron, serum ferritin, and transferrin saturability of the women between group B and group C(P>0.05), but which of the women between group B and group C were all significantly higher than those of the women in group A(P<0.05). The incidence of constipation of the women in group C was 6%, which was significantly lower than that(24%) of the women in group A or that(26%) of the women in group B(P<0.05). There was no significant difference in perinatal outcomes of the women among the three groups(P>0.05). Conclusion: The anemia situation of the pregnant with IDA can be improved by routine iron supplementation treatment, and Jianpi shengxue granules used for the treatment additionally can further improve the therapeutic effect of anemia with good safety. The constipation status of the pregnant women can be improved by sodium ferrous fumarate capsule.
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