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Abstract To analyze the clinical efficacy of methotrexate(MTX) combined with hysteroscopy for treating women with endogenous cesarean scar pregnancy(CSP). Methods: 72 women with endogenous CSP were selected and were divided into control group and observation group according to the principles of voluntary selection. The women in the control group were given the treatment of methotrexate combined with curettage, and the women in the observation were given the treatment of methotrexate combined with hysteroscopy. The clinical curative effect of the women was compared between the two groups, and the clinical curative effect was also compared among the women with different size of the lesions. Results: The total effective rate(97.4%) of the women in the observation group was significant higher than that(84.9%) of the women in the control group(P=0.020). The intraoperative blood loss(72.0±11.6ml), the time of blood β-hCG level returned to normal(20.1±8.0d), and the time of postoperative hospital stay(11.6±3.3d) of the women in the observation group were significant lower than those of the women in the control group(P=0.000, 0.002, and 0.010). In the observation group, the total effective rate(100%) of the women with lesion diameter ≤2.5cm was significant higher than that(90.9%) of the women with lesion diameter >2.5cm(P=0.010). Conclusion: The methotrexate combined with hysteroscopy for treating endogenous CSP has good curative effectiveness, especially for those women with lesion diameter ≤2.5cm, which can reduce intraoperative massive haemorrhage occurrence and is beneficial to postoperative recovery.
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