|
Abstract To analyze the clinical efficacy and safety of pituitrin combined with laparoscopic myomectomy for treating patients with benign hysteromyoma. Methods: A total of 332 patients with benign hysteromyoma who underwent laparoscopic myomectomy were selected and were randomly divided into study group and control group by random number table method from March 2018 to March 2020. 182patients in the study group were given one-time uterus injection of pituitrin 12U during operation, and 150 patients in the control group were given one-time uterus injection of oxytocin 20U during operation. The efficacy and safety of the patients were compared between the two groups. Results: The operating time (88.0±24.2 min), the intraoperative blood loss (57.8±20.8 ml), and the hospital stay time (4.9±1.1d) of the patients in the study group were all significant shorter than those (111.5±28.9min, 197.3±31.0ml, and 8.8±1.4d)) of the patients in the control group (P<0.05), but the postoperative exhaust time of the patients had no significant different between the two groups (P>0.05). The values of systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) of the patients in the two groups had been volatility significantly after medicine used (P<0.05). 5 min after medicine used, the SBP value of the patients in the study group was significant higher than that of the patients in the control group, but the values of DBP and HR of the patients in the study group were significant lower than those of the patients in the control group (P<0.05), and the values of SBP, DBP, and HR of the patients at rest time had no significant different between the two groups (P>0.05). The incidence of postoperative infection (2.8%) of the patients in the study group was significant lower than that (8.0%) of the patients in the control group (P<0.05), but the rates of postoperative hematoma, fever, delayed healing, and other complications, such as low blood pressure of the patients had no significant different between the two groups (P>0.05). Conclusion: Pituitrin or oxytocin combined with laparoscopic myomectomy for treating the patients with benign uterine fibroids has definite effect. However, pituitrin has advantages in reducing bleeding, shortening operation time, and reducing postoperative infection, which is worthy of clinical application.
|
|
|
|
|
|
