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| Effect of Zishenyangluan decoction for treating infertility women because of thin endometrium on the improvement of their endometrial receptivity, ovarian blood flow, and pregnancy rate |
| The Second People's Hospital of Haining, Zhejiang Province, 314419 |
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Abstract To investigate the effect of Zishenyangluan decoction for treating infertility women because of thin endometrium on the improvement of their endometrial receptivity, ovarian blood flow, and pregnancy rate. Methods: 98 infertility women because of thin endometrium were selected and divided into two groups （49 cases in each group）by random number table method from December 2018 to December 2019. The women in the control group were treated with estradiol valerate and dydrogesterone tablets, and the women in the observation group were given Zishenyangluan decoction on the basis treatment of the women in the control group. The endometrial receptivity, ovarian blood flow, pregnancy rate, and drug adverse reactions rate of the women were compared between the two groups. Results：After treatment, menstrual score and endometrial thickness of the women in both groups had increased significantly, and the improvement of which of the women in the observation group were significant better than those of the women in the control group (P＜0.05). The endometrium type of the women in the two groups were type A mainly, and the proportion of type A endometrium of the women in the observation group was significant more than that of the women in the control group (P＜0.05). There were no differences in the proportions of type B and type C endometrium between the two groups (P＞0.05). The peak flow systolic velocity (PSV) of uterine artery of the women in both groups had increased significantly, while the values of resistance index (RI) and pulse index (PI) of the women in both groups had decreased significantly, and the improvement of which of the women in the observation group was significant better than that of the women in the control group (P＜0.05). The pregnant success rate (36.7%) of the women in the observation group was significant higher than that (18.4%) of the women in the control group (P＜0.05). Adverse reactions of the women in the two groups were all mild, and which had no significant difference (6.1% vs. 6.1%) between the two groups (P＞0.05). Conclusion: Zishenyangluan decoction adjuvant therapy of infertility women because of thin endometrium can effectively improve the endometrial receptivity and ovarian blood flow parameters, and can increase the pregnancy rate with safety and effectiveness.
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