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| The influence of different cervical conization range on cervical dysfunction and pregnancy outcomes |
| Baoshan Integrated Chinese and Western Medicine Hospital, Shanghai, 200643 |
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Abstract To investigate the influence of different cervical conization range of women on their cervical dysfunction and pregnancy outcomes. Methods: Clinical data of 356 women with high level cervical intraepithelial neoplasia (CIN) II or CIN III were analyzed retrospectively. These women were all treated by cervical conization, and the influence of different cervical conization range on their cervical dysfunction and pregnancy outcomes were analyzed. Results: The length of cervix of all women had shortened significantly and the width of cervical canal of all women was significant enlargement after operation (P<0.05), but there was no significant change in the width of the cervical internal orifice of these women after operation (P>0.05). The volume of conization of women with cervical shortening was significant larger than that of women without cervical shortening, the volume of conization of women with cervical relaxation was significant larger than that of women without cervical relaxation, and the depth of conization of women with cervical stenosis was significant more than that of women without cervical stenosis (P<0.05). According to the scope of conization, 152 women were divided into 45 cases after large conization in group A and 107 cases after small conization in group B. The gestional weeks when delivery and rate of spontaneous labor of women in group A (37.4±1.8 weeks and 13.3%) was significant less than that (38.1±1.5 weeks and 29.0%) of women in group B, and the preterm delivery rate and the cesarean section rate of women in group A (15.6% and 82.2%) were significant lower than those (5.6% and 64.5%) of women in group B (all P<0.05). Conclusion: Too large scope of conization has adverse effects on cervical function and pregnancy outcomes of women, so the scope of conization should be strictly controlled in clinic practice.
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