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| Analysis of cervical length change, pregnancy rate and adverse pregnancy outcomes in young patients after LEEP |
| The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, 450052 |
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Abstract To investigate the cervical length change of young patients after loop electrosurgical excisional procedure (LEEP), and to study its influence on pregnancy outcomes. Methods: 105 patients with cenvical squamous intraepithelial lesion (CIN) underwent LEEP were selected in study group, and 42 healthy pregnant women underwent prenatal physical examinations were selected in control group from February 2018 to February 2019. The cervical length of women in the study group were compared between before LEEP and 6 months after LEEP. The rates of pregnancy and adverse pregnancy outcomes of women were compared between the two groups. Results: At 6 months after LEEP in the study group, the cervical length (28.13±2.36mm) of patients was significant shorter than that (29.76±2.45mm) before LEEP. The cervical length (28.2± 2.3mm) of patients in the study group before pregnancy was significant shorter than that (29.9 ±2.3mm) of patients in the control group (P＜0.05). The rates of late abortion, preterm birth rate, and membranes premature rupture of patients in the study group after operation were 18.0%, 41.0%, and 19.1%, respectively, which were significant higher than those(2.6%, 4.8%, and 2.4%, respectively) of patients in the control group (P＜0.05). Conclusion: The cervical length of young patients with LEEP becomes shorter, which has no effect on fertility function, while the incidences of adverse outcomes, such as abortion during the third trimester of pregnancy, preterm birth, and preterm rupture of membranes, may be increase, so LEEP indications should be confirmed for patients who want to giving birth， and their cervical tissue should be saved as much as possible during LEEP for improving their chances of giving birth.
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