To investigate the effect different treatments of cervical lesions of pregnant women on their pregnancy outcomes and delivery mode. Methods: The clinical data of 870 pregnant women after treatment of cervical lesions from March 2012 to March 2018 were retrospectively analyzed. According to the different treatment of cervical lesions, these women were divided into Group A (207 women had received the loop electrosurgical excision procedure (LEEP), group B (105 women had received the cold knife conization (CKC), group C (302 women had received intensity focused ultrasound (IFU), and group D (256 women had received physical laser). Meanwhile, 82 healthy pregnant women were randomly selected in control group during the same period. The delivery mode, pregnancy outcomes, rate of complications during delivery, time of the total stage of labor, the cervical length in 22-24 gestational weeks, and the degree of cervical stenosis of women, and neonatal weight, length, Apgar score were compared among these groups. Results: The cesarean section rate of women in the control group, group D, group C, group A, and group B had increased in turn (P<0.05). The incidences of premature delivery and premature rupture of membranes of women in group A, B, C, and D were significant  higher than those of women in the control group (P<0.05). The incidence of cervical laceration, uterine rupture, postpartum hemorrhage, or postpartum infection of women in group B was the highest (P<0.05). There were significant different in the neonatal weight, length, and Apgar score among these groups (P<0.05). The total stage of labor time and cervical stenosis degree of women in the control group, group D, group C, group A, and group B had increased in turn (P<0.05). The cervical length of women in 22-24 gestational weeks in the control group, group D, group C, group A, and group B had shorted in turn (P<0.05). Conclusion: The treatment of the cervical lesions can maybe increase the rate of cesarean section, premature delivery, premature rupture of membranes, and infection of women after pregnancy, which suggests anti-infective treatment should be strengthened during treatment of the cervical lesions can, and the appropriate delivery mode should be given according to the situation of pregnant women for decreasing their cesarean section rate.