To explore the contraception effect of medicated γ intrauterine device (IUD) and uterine shape copper 200 IUD inserted immediately after induced abortion. Methods: 168 women wanted IUD inserted after abortion immediately were selected and were divided into group A (94 women with activeγshape IUD inserted ) and group B (74 women with uterine shape copper 200 IUD inserted) from January 2015 to June 2018. The clinical contraception effect of the women was compared between the two groups. Results: There were no significant difference in the rates of expulsion and moved down of IUD, and the rate of pregnancy with IUD in situ of women between the two groups. The IUD continuation rate of women in group A was 93.6%, which had no significant different from that (90.5%) of women in group B (P>0.05). The total incidence of adverse reactions of women in group A was 16.0%, which was significant lower than that (33.8%) of women in group B (P<0.05). The levels of vascular endothelial growth factor in uterine cavity flushing fluid of women in group A in 1 month and 3 months after IUD inserted was 187.28±23.39ng/ml and 102.29±21.10ng/ml, which were significant lower than those (220.22±25.51ng/ml and 154.48±26.61ng/ml) of women  in  group B. And the levels of interleukin 6 in uterine cavity flushing fluid of women in group A in 1 month and 3 months after IUD inserted were 64.45±21.10pg/ml and 44.50±18.21pg/ml, which were significant lower than those (98.82±18.82pg/ml or 67.71±17.71pg/ml) of women in group B (All P<0.05). Conclusion: The contraceptive effect of both medicated γ IUD and uterine shape copper 200 IUD inserted after abortion immediately is good, but the adverse reaction of medicated γ IUD is less and has little effect on the expression of inflammatory factors in uterine fluid of women.