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| The changes of hemoglobin value and serum ferritin level of pregnant women with thalassemia and their influence on maternal and infant outcomes |
| Guangzhou Baiyun Maternal and Child Health Care Hospital, Guangdong Province,510410 |
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Abstract Objective: To investigate the changes of the hemoglobin (HGB) value and serum ferritin (SF) level of pregnant women with thalassemia, and to study their influence on maternal and infant outcomes. Methods: 67 pregnant women with thalassemia from December 2017 to December 2018 were selected in study group, and 67 normal pregnant women were selected in control group during the same period. The changes of HGB value and SF level of women during pregnancy, and maternal and infant outcomes of women were compared between the two groups. Results：The change of HGB value of women in the study group during different pregnant period was significant more than that of women in the control group, and the degree of decreased of HGB value of women in the study group during pregnancy was 15.8±0.4 g/L, which was significant less than that (28.9±1.6 g/L) of women in the control group (P<0.05). There was no significant difference in the change of SF level of women during the first trimester pregnancy between the two groups (P>0.05). The degree of decreased of SF level of women during the second and third trimester pregnancy in the study group was 75.5±5.2 ng/ml, which was significant less than that (81.9±6.9 ng/ml) of women in the control group (P<0.05). The rate of maternal and infant adverse outcomes in the study group was significant lower than that of women in the control group (P<0.05). Conclusion: HGB value of women with thalassemia during different pregnant period decreases to different degrees, and their SF level decreases to different degrees during the second and third trimester of pregnancy, both the decreasing of HGB value and SF level of women during pregnancy have adverse effects on maternal and infant outcomes.
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