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| Analysis of blood glucose status and high risk factors of pregnant women with gestational diabetes mellitus |
| Pingdingshan Maternal and Child Health Care Hospital, Henan Province, 467000 |
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Abstract Objective: To observe the blood glucose level of women with history gestational diabetes mellitus (GDM) during pregnancy again, and to analyze the risk factors of recurrent GDM. Methods: 138 pregnant women with history GDM were selected as the research objects, and were divided into study group and control group according to the value of glucose tolerance test (OGTT) during pregnancy. The the value of OGTT and clinical index of women were compared between the two groups and between their two-time pregnancy. And the risk factors of recurrent GDM of pregnant women were analyzed. Results: There were no significant different in levels of fasting blood glucose (FPG), 1hPG and 2hPG of women between the two-time pregnancy (P>0.05). The proportions of abnormal FPGv+1h PG and abnormal FPG+2hPG during this pregnancy of women with recurrent GDM were significant higher than those of women during previous pregnancy (P<0.05). The rates of women ≥35 years old, BMI ≥25kg/m2 before this pregnancy, their first-degree relatives with diabetes, and abnormal FPGv+1h PG and/or abnormal FPG+2h PG during previous pregnancy of women in the study group were significant higher than those of women in the control group (P<0.05). There were no statistically significant different in the proportions of ethnic minorities and adverse pregnancy history, and interval time of two-time pregnancy, FPG value in previous pregnancy, and rates of poor blood glucose controlled and insulin used during previous pregnany of women between the two groups (P>0.05). The women ≥35 years old, BMI≥25kg/m2 before this pregnancy, the level of 2h PG≥9.0mmol/L, and the abnormal FPG+1h PG and/or FPG+2h PG during previous pregnancy were the influencing factors of GDM recurrence (P<0.05). Conclusion: The pregnant women age, BMI before this pregnancy, the level of 2h PG and the abnormal FPG+1h PG and/or FPG+2h PG during previous pregnancy may influence GDM recurrence, so it is should be paid more attention to in clinical practice.
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