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| Influence of length of anesthesia on the incidence of infection and stress indicators of women after cesarean section |
| The Second People's Hospital of Nanyang City, Henan Province, 473000 |
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Abstract Objective: To investigate the influence of length of anesthesia on the incidence of infection and stress indicators of women after cesarean section. Methods: The clinical data of 1,200 women who exprienced cesarean section from January 30, 2016 to April 30, 2019 were analyzed retrospectively. The incidence of postoperative infection, the characteristics of postoperative infection, and the distribution of pathogens of all included women were observed. The influence of anesthesia time on the incidence of infection, and the changes of levels of norepinephrine, cortisol and blood glucose of women were also analyzed. Results: There were 70 (5.8%) women with postoperative infection, wich included 44.3% women with incision infections and 22.9%women with urinary system infections. The postoperative infection caused by gram-positive bacteria (mainly staphylococcus aureus) accounted for 55.6%, and the postoperative infection caused by gram-positive bacteria (mainly escherichia coli) accounted for 44.4%. The postoperative infection rate of women with maternal hemorrhage ≥200ml, intraoperative blood transfusion, anesthesia time ≥1h, no antibiotics used before operation, invasive examination ≥5 times, or with premature rupture of membranes had increased significantly (P<0.05). Multivariate analysis showed that intraoperative bleeding ≥200ml, anesthesia time ≥1h, and invasive examination ≥5 times were risk factors for postoperative infection, and prophylactic antibiotics used before cesarean section were protective factors (P<0.05). The levels of norepinephrine, cortisol and blood glucose of women with anesthesia time ≥1h were significant higher than those of women with anesthesia time <1h (P<0.05). Conclusion: The anesthesia time during cesarean section over 1h can increase the stress level and infection incidence of women after cesarean section, so shortening anesthesia time and prophylactic antibiotics used before cesarean section can reduce the postoperative infection occurance effectivly.
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