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| Risk factors of ectopic pregnancy of women undergone in vitro fertilization-embryo transfer |
| Qinghai Red Cross Hospital, Xining, Qinghai Province, 810000 |
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Abstract Objective: To investigate the risk factors of ectopic pregnancy of women undergone in vitro fertilization-embryo transfer (IVF-ET). Methods: 990 women who had received IVF-ET were selected in this study from October 30, 2014 to October 30, 2018, which included 450 women received fresh embryo transplantion (25 with ectopic pregnancy) and 440 women received frozen transplantation (22 with ectopic pregnancy). The risk factors of ectopic pregnancy of women received fresh embryo transplantion or frozen embryo transplantation were analyzed. Results: Among the women received fresh embryo transplantation, the history of abortion, curettage and pelvic surgery, the total Gn dosage, and estradiol level on trigger day of women with ectopic pregnancy were significant higher than those of women with intrauterine pregnancy (P<0.05). Multivariate analysis showed that the history of curettage and pelvic surgery, total Gn dosage, or estradiol level of women on trigger day were independent risk factor of ectopic pregnancy for women received fresh embryo transplantation (P<0.05). Among women received frozen embryo transfer, the proportions of abortion history, ectopic pregnancy history, curettage history, and history of pelvic surgery of women with ectopic pregnancy were signifficent higher than those of women with intrauterine pregnancy. The number of transplanted embryos and the endometrial thickness on embryo transplantion day of women with ectopic pregnancy were significant less than those of women with intrauterine pregnancy (P<0.05). Multivariate analysis showed that the history of curettage, history of pelvic surgery, or number of transplanted embryos was independent risk factor of ectopic pregnancy for women received frozen embryo transplantion. Conclusion: The history of curettage, history of pelvic surgery, total dosage of Gn, and high estradiol level on the trigger day are risk factors of ectopic pregnancy for women receiving fresh embryo transplantion. History of curettage, history of pelvic surgery, and number of transplanted embryo are risk factors of ectopic pregnancy for women receiving frozen embryo transplantion.
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