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| Analysis of risk factors and pregnancy outcomes of women with gestational diabetes mellitus in Yili region of Xinjiang |
| The Fourth Division Hospital of Xinjiang Production and Construction Corps, Yining, Xinjiang, 835000 |
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Abstract Objective: To investigate the prevalence and risk factors of gestational diabetes mellitus (GDM) in Yili region of Xinjiang, and to analyze its influence on pregnancy outcomes. Methods: 4 hospitals in Yili region of Xinjiang were selected by systematic and cluster sampling method. Clinical data of 6434 pregnant women who attended prenatal care and delivered in these four hospitals were collected. GDM was diagnosed according to International Association of Diabetes and Pregnancy Study Groups (IADPSG).The disease characteristics of GDM were analyzed and the pregnancy outcomes of all included pregnant women were followed up. Results: The prevalence of GDM in Yili region was 6.6% (422/6434). The age≥35 years old, family history of diabetes mellitus, pre-pregnancy overweight or obesity, high education level, maternal, urban household registration, or mental work were the independent risk factor for GDM (P<0.05). The the delivery gestational weeks of women with GDM was earlier than that of women without GDM (P<0.05). The rates of cesarean section, premature labor, anemia, hypertensive disorder complicating pregnancy (PHD), and hydramnios of women with GDM were significant higher than those of women without GDM, and those of GDM women with poor glycemic control were also significant higher than those of GDM women with good glycemic control (P<0.05). There were no significant different in rates of premature rupture of membranes and postpartum hemorrhage between the women with GDM and the women without GDM (P>0.05). The incidences of fetus with large for gestalional age (LGA), fetal growth restriction (FGR), macrosomia, and hypoglycemia of neonates of women with GDM were significant higher than those of women without GDM, and those of GDM women with poor glycemic control were also significant higher than those of GDM women with good glycemic control (P<0.05). There were no significant different int the incidences of fetal distress and congenital malformation between the women with GDM and the women without GDM (P>0.05). Conclusion: The prevalence of GDM in Yili region of Xinjiang was at middle intermediate level of China and has population differences. It should be improved the level of perinatal healthcare of women from Yili region by targeted management measures for preventing GDM.
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