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| The value of monitoring endometrial thickness by ultrasound combined with levels o fβhCG and progesterone for diagnosing women with early ectopic pregnancy |
| 1.Chengmai County Chinese Medicine Hospital, Hainan Province, 571900；2.Hainan Provincial Hospital of Traditional Chinese Medicine |
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Abstract Objective: To explore the value of monitoring endometrial thickness by ultrasound combined with levels of βhCG and progesterone (P) for diagnosing women with early ectopic pregnancy. Methods: 84 women with early ectopic pregnancy (group A), 82 women with spontaneous abortions (group B), and 80 normal pregnant women (group C) were enrolled in this study from May 2016 to September 2018. The diagnostic accuracy was compared among different indicators, and ROC curve was used for evaluating the diagnostic efficiency. Results: The levels of β hCG and P, and endometrial thickness of women in group A were the lowest among the three groups (P<0.05). The ROC curve analysis showed that the cut off value of βhCG level for diagnosing ectopic pregnancy was 821.09 U/L and AUC was 0.752 (P=0.031), and its sensitivity and specificity were 83.2% and 92.1%. The cut off value of P level for diagnosing ectopic pregnancy was 18.09 nmol/L and AUC was 0.010 (P=0.008), and its sensitivity and specificity were 81.8% and 90.3%. The cut off value of endometrial thickness for diagnosing ectopic pregnancy was 6.70 mm and AUC was 0.704 (P=0.001), and its sensitivity and specificity were 73.3% and 81.7%. The coincidence rate of endometrial thickness by ultrasound combined with levels of βhCG and P for diagnosing women with early ectopic pregnancy was the highest (P<0.05). Conclusion: The endometrial thickness by ultrasound combined with levels ofβhCG and P can significantly improve the early diagnosis rate of ectopic pregnancy, and can reduce missed diagnosis and misdiagnosis.
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