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| Clinical analysis of hysteroscopy combined with laparoscopy for diagnosing and treating unexplained infertility women |
| Zhejiang Provincial People’s Hospital (People’s Hospital Affiliated to Hangzhou Medical College), Zhejiang Province, 310014 |
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Abstract Objective: To explore the value of hysteroscopy combined with laparoscopy for diagnosing and treating unexplained infertility women. Methods: A retrospective study was conducted on the unexplained infertility women from January 2014 to December 2017. The unexplained infertility women were divided into the study group and the control group according to whether the women treated by hysteroscopy combined with laparoscopy. Results: 67 women in the study group were given hysteroscopy combined with laparoscopy surgical, and 103 women in the control group hadn’t experienced surgical. There were no significant differences in age, BMI, type and duration of infertility between the two groups. 98.1% of women in the study group had been found one or more causes that might be related to their infertility. The rates of positive HCG, clinical pregnancy, and continued pregnancy of the women who underwent in vivo fertilization in the study group were significant higher than those of women in the control group (52.2% VS. 22.3%, 52.2% VS. 20.4%, 47.8% VS. 16.0%, P<0.05). The average time of women who underwent in vivo fertilization (IVF-ET) became pregnant women after operation was (4.0±2.6) months. The clinical pregnancy rate was 37.3% within half a year after surgery, which was significant higher than that (18.5%) in 6-12 months after surgery (P<0.05). Among the women without pregnancy who had received IVF-ET after 6.5±1.7 months, there were no significant difference in the rates of positive HCG, clinical pregnancy, and continuous pregnancy between the two groups (76.9% VS. 72.4%, 61.5% VS. 69.0%, 53.9% VS. 48.3%, P>0.05). Logistic regression analysis suggested that hysteroscopy combined with laparoscopy was the independent effect factor for pregnancy of women with unexplained infertility. Conclusion: The hysteroscopy combined with laparoscopy should be used in women with unexplained infertility, which can significantly increase the rate of pregnancy. The women with unexplained infertility should be try to get pregnancy within 6 months after hysteroscopy combined with laparoscopy surgical, and as for those women without pregnancy, IVF-ET should be used.
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