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Abstract Objective: To investigate the effect of dexmedetomidine used in spinal anesthesia for preventing chill and traction response of women during cesarean section. Methods: 68 women with cesarean section were divided into two groups (34 cases in each group) by random number table. The women in both groups underwent cesarean section under spinal anesthesia. After anesthesia, the women in control group were given intrathecal normal saline, and the women in observation group were given intrathecal dexmedetomidine hydrochloride. The hemodynamic changes at different time, the intraoperative sedation levels, and rates of chills and traction reactions of women were compared between the two groups. Results: There were no significant different in the sensory block time, the highest level of sensory block, the time of surgery preparation, the time from skin incision to delivery, and the time from uterine incision to delivery between the two groups (P>0.05). The recovery time of exercise block of women in observation group was significant shorter than that of women in control group (P<0.05). There were no significant different in values of SBP, DBP and HR of women at T0, T1, T2 and T3 time between the two groups (P>0.05). The incidence of chills, the proportion of chills 2-3 class, the incidences traction reaction, and the total rate of adverse reaction of women in observation group were significant lower than those of women in control group (P<0.05). The sedation level of women in observation group was better than that of women in control group (P<0.05). Conclusion: The using of dexmedetomidine after intrauterine spinal anesthesia during cesarean has good sedative effect, which can prevent chills and traction response during anesthesia, improve the recovery of motor block, and doesn’t affect hemodynamics.
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