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| Effect of syndrome differentiation and pretreatment on pregnancy outcomes of women with history early spontaneous abortions |
| 1.Beijing Tongrentang Hospital of Traditional Chinese Medicine, Beijing, 100051; 2.Beijing Hospital of TCM Affiliated to Capital University of Medical Science |
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Abstract Objective: To observe the effect of traditional Chinese medicine (TCM) syndrome differentiation and pretreatment on pregnancy outcomes of women with history of early spontaneous abortion. Methods: 160 women with history early spontaneous abortion were divided into study group and control group randomly. The pretreatment of TCM started given to women who planned to pregnancy three months before in study group, and vitamin E and folic acid were also given. For the women in control group, vitamin E and folic acid were given only at the same time. After pregnancy, all women in both groups had been given Chinese medicine, progesterone soft capsules, and chorionic gonadotropin (HCG)HCG for preventing miscarriage. The symptoms during gestation, serum levels of HCG, progesterone (P) and estradiol (E2) were compared between the two groups. Besides, the pregnancy outcomes of all women were also followed up. Results: The effective rate of women in study group(88.7% in 97 cases ) was significant higher than that of women(73.8%) in control group（P<0.05）. The symptom scores of threatened abortion in the first trimester early pregnancy of women in study group (50.5 feb) was significant lower than that of women (73.7 feb) in control group (P<0.05). The level of serum HCG, progesterone and estradiol of the first trimester early pregnant women in study group were significant higher than those of women in control group (P<0.05). Conclusion: TCM syndrome differentiation and pretreatment of for women who want to pregnancy can significantly improve the pregnant outcomes of women with history spontaneous abortions in the first trimester pregnancy.
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