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| The correlation between pregnant outcome and the changes of electrocardiogram of older pregnant women during late stage pregnancy |
| People's Hospital of Wuyi County, Zhejiang |
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Abstract Objective: To explore the correlation of the pregnant outcome with the changes of electrocardiogram（ECG）of older pregnant women during late stage pregnancy. Methods：From February 2015 to February 2017, 378 older pregnant women( equal to or over 35 years old) who admitted in people's hospital of Wuyi county for prenatal examination and labor were selected in observation group, and during the same period, 370 pregnant women (less than 35 years old) were in control group. Women in both groups were examined by electrocardiogram during late stage pregnancy. The rate of abnormal ECG, cardiac arrhythmia, and pregnant outcome were compared between the two groups. Results：The incidence of abnormal ECG of women in observation group was 30.4%, and that of women in control group was 12.6%, which had statistical significance different (P< 0.05). The incidence of arrhythmia, short PR interphase, ST segment depression, left bias of electric axis, and low voltage of conduction of women in observation group were significant higher than those of women in control group. The rate of sinus tachycardia, sinus arrhythmia and room premature beat of women in observation group were significantly higher than those of women in control group (P<0.05)，but there were no differences in the incidence of sinus bradycardia, indoor conduction block and ventricular premature beats between the two groups (P > 0.05). In pregnant women with normal ECG, there were no significant difference in pregnant outcomes and neonatal birth weight between the two groups (P > 0.05), the incidence of premature infants in observation group was significant higher than that in control groups (P< 0.05). The incidence of abortion, premature birth, and low birth weight in observation group were significant higher than those in control groups (P< 0.05). Conclusion：The incidence of abnormal ECG of older women during late pregnancy increases. And the incidence of abortion, premature delivery and low birth weight of newborns of older pregnant women are also higher than those of pregnant women at the right age. Prenatal ECG monitoring for older pregnant women should be strengthened to ensure the safety of maternal and child.
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