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Abstract Objective: To observe the predictive effect of serum progesterone detection combined with uterine spiral arterial flow ultrasound on pregnancy outcome in patients with threatened abortion. Methods: 400 women with early pregnancy from Chongqing Banan district people's hospital were selected as research subjects between August 2015 and August 2017, which Included 200 women with normal pregnancy (normal pregnant group), 138 early threatened abortion women with tocolysis successful (tocolysis success group), 62 early threatened abortion women with tocolysis failure (tocolysis failure group). Serum progesterone of all pregnant women in the three groups was detected. PI, RI and S/D of uterine spiral and uterine arteries of women in the three groups were detected by color doppler ultrasonography. Serum progesterone and uterine spiral artery blood flow index were compared among the three groups. Results: There was difference in serum progesterone level of women among the three groups (F=10.593, P=0.000<0.05), and there was no difference in PI, RI and S/D of uterine artery among the three groups (F=1.028, 1.359 and 0.948；P=0.168, 0.105 and 0.199>0.05), but there was difference in PI, RI and S/D of uterine spiral artery among the three groups (F=11.514, 9.329 and 2.779；P=0.000, 0.000 and 0.023<0.05). The sensitivity, specificity and accuracy of serum progesterone combined with PI and RI of uterine spiral artery to predict the pregnancy outcome of early threatened abortion were 85.48%, 97.63% and 95.75%, respectively. Conclusion: The serum progesterone value and uterine spiral arterial blood flow index in pregnant women with early threatened abortion are different from those of normal pregnant women. The value of serum progesterone, PI and RI of uterus spiral artery can be used as a diagnostic and prognostic indicator for early threatened abortion. The using of combination of these three indicators can improve the prediction specificity and accuracy of pregnant outcome of women with early threatened abortion, so it should be paid more attention to.
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