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An analysis of influencing factors on the outcome of women with poor ovarian responders |
Reproductive Medical Center, Department of Gynaecology and Obstetrics, General Hospital of Tianjin Medical University, Tianjin, 300052 |
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Abstract Objective: To explore influencing factors on the clinical outcome of women with poor ovarian responders during in vitro fertilizationembryo transfer (IVFET) or intracytoplasmic sperm injection (ICSI). Methods: A retrospective analysis was conducted and the data was collected from 122 IVFET/ICSI cycle patients with poor ovarian response from the reproductive medicine center of the general hospital of Tianjin medical university between Jan. 2012 and Sep. 2016. All included patient were divided into pregnant group (n=26) and nonpregnant group (n=96). And all the patients were also divided into group A (<35 years old, n=21) , group B(3540 years old, n=36)and group C (>40 years old, n=65)according to their age. Results: There were significant different in age and endometrial thickness between the pregnant group and the nonpregnant group(P<0.05). The implantation rate and pregnancy rate of patients over 40 years old decreased significantly. Logistic regression analysis results showed that age and endometrial thickness had contributed to clinical outcome. Conclusion: Age and the endometrial thickness are the important influencing factors on the outcome of women with poor ovarian responders in IVFET/ICSI.
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