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| An analysis of diseases cisposition and trends of 18897 congenital disabled children of Sichuan province based on medical authentication by ICD10 |
1.National Research Institute for Family Planning, Beijing, 100081；2. National Center for Human Genetic Resources；3. Sichuan Family Planning Research Institute, Chengdu University of Traditional Chinese Medicine；
4. Health and Family Planning Commission of Sichuan Province；5. Graduate School of Peking Union Medical College |
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Abstract Objective: To analysis medical authentication data of congenital disabled children, and to understand the cisposition and trend of congenital diseases. Methods: Based on standard ICD10 diseases automatic classification process, 21059 diagnosed congenital diseases were coded corresponding to 18897 disabled children applied for medical authentication by prefectural level between 2004 and 2015 in Sichuan province, and SAS 9.2 and R 3.3.3 statistics software were used for analyzing the basic demographic characteristics, as well as disease cisposition and trend of these congenital disabled children during 12 years by general, region and annual. Results: Average approval ratio of medical authentication for congenital disabled children in Sichuan province between 2004 and 2015 was 83.3%, and average age of them when applied for medical authentication was 7.7 years old, male accounted for 59.2%, and children from rural area accounted for 77.5%. There were 131 congenital diseases diagnosed, and the most popular ten congenital diseases were congenital malformations of heart, congenital malformations of heart septum, congenital malformations of brain, undescended testicle, congenital musculoskeletal deformities, Down's syndrome, congenital musculoskeletal deformities of head, face, spine and chest, reduction defects of upper limb, congenital deformities of hip and cleft palate with cleft lip. The region cisposition showed that the most popular congenital disease in Luzhou city was congenital malformations of brain, but the most popular congenital disease in the other cities of Sichuan province were congenital heart disease. Annual trend analysis results showed that the proportion of Down's syndrome, congenital malformations of heart septum, and thalassaemia were in the rising trend, while the proportion of congenital musculoskeletal deformities, congenital malformations of brain, and undescended testicle were in the downward trend. Conclusion: Congenital heart disease, congenital malformations of brain, undescended testicle, congenital musculoskeletal deformities, Down's syndrome were high incidence congenital diseases in disabled children in the medical authentication of Sichuan province. In order to reduce the incidence and disability rates of children’s congenital diseases, it is necessary to work out effective prevention and cure strategies for the congenital diseases in the rising trend such as Down's syndrome, congenital malformations of heart septum, and thalassaemia.
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