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| Effect of Baofukang suppository combined with estrogen ointment in treating senile vaginitis and its influence on hormone level of patients |
| Department of gynaecology and obstetrics, Wuhan Children's Hospital（Wuhan Maternal and Child Healthcare Hospital）, Tongji Medical College, Huazhong University of Science & Technology, Hubei, 430014 |
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Abstract Objective: To investigate the effect of Baofukang suppository combined with estrogen ointment on treating senile vaginitis, and to explore its influence on hormone levels of patients. Methods: A total of 168 elderly patients with vaginitis admitted to Wuhan Children's Hospital were enrolled in this study. They were divided into three groups (56 cases in each group) by random number table method. The patients in Baofukang suppository group were given Baofukang suppository, the patients in estrogen ointment group were given hormone ointment, and the patients in combination therapy group were given Baofukang suppository combined with estrogen ointment. The treatment effect, the hormone level of patients, and rate of adverse reactions of drug were compared among the three groups. Results: The total effective rate (98.2%) of patients in combination group was significant higher than that of patients in Baofukang suppository group (83.9%) and estrogen ointment group (85.7%). The levels of E2, FSH, P and LH of patients were significantly improved after treatment, and the improvement degree of hormone levels of patients in combination group was higher than the that of patients in other two groups (P<0.05). The incidence of adverse reactions of patients in the three groups had no significant difference (P>0.05). Conclusion: Baofukang suppository or estrogen ointment used alone has a positive therapeutic effect on senile vaginitis. However, Baofukang suppository combined estrogen ointment treating senile vaginitis can achieve better therapeutic effect, can regulate hormone levels better, and is safety, so it is worthy of clinical application.
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