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Zhao Jun,Li Xia,Tian Aiping,Zhang Hongguang,Dai Qiaoyun,Peng Zuoqi,Wang Yuanyuan,Ma Xu
To implement automatic classification for ICD-10 nomenclature by introducing ICD-10 as classification criteria for diseases of sick and disabled children. Methods: A total of 62 225 diagnoses for 53 632 children who took part in the medical identification between 2004 and 2011 in Sichuan Province were collected by the medical verification management system for sick and disable children. A standardized process of automatic classification for ICD-10 nomenclature of sick and disabled children were implemented by building an ICD-10 matching code library as well as regularizing code matching principles. Results: Barbarism of writing and naming was found and a matching code extension library based on existed ICD and FAD code libraries was established. The overall matching rate reached 96.58% with the standardized process. Conclusion: With the help of standardized process of automatic classification for ICD-10 nomenclature of sick and disabled children, the workload of manual classification could be reduced and the intelligent statistical analysis could be performed, laying the foundation for fully sharing and utilizing identification documents of sick and disabled children.
2013 Vol. 21 (7): 436-440 [Abstract]（
63
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Wang Qianxing,Lang Nan,He Bin,Xu Xiangbo,Wang Jiedong
To explore effects of progesterone replacement in different time after progesterone withdrawal on endometrial stromal cells apoptosis in mice menstrual-like model. Methods: Based on determined of the critical period of progesterone withdrawal precedes endometrial breakdown and shedding in mouse menstrual-like model, progesterone added back to mouse before (at 12h) or after (at 16h) the critical period(progesterone withdrawal). Mouse uterine horns were collected for the detection of mouse endometrial stromal cell apoptosis in situ by TUNEL technology. Moreover, expressions of apoptotic-related proteins, Bcl-2, Bax and Caspase-3, were evaluated by Western Blotting in mouse endometrial stromal cells. Results: When progesterone added back to the mouse at 12h after progesterone withdrawal, the number of apoptotic cells was significantly reduced in mouse endometrial stromal cells but that was not decreased obviously when progesterone was replaced at 16h. The expression of Bcl-2, a antiapoptotic protein, in 12h replacement group was significantly higher than those of 16h replacement group and the control group (P<0.01). While there was no significant difference between the latter two groups (P>0.05). As for proapoptotic protein, expressions of Bax and Caspase-3 in 12h replacement group were significantly lower than those in 16h replacement group and the control group (P all >0.05), while no differences were found between the latter two groups(P all <0.01). Conclusion: Before the critical period of precedes endometrial breakdown and shedding, i.e., progesterone replacement at 12h after progesterone withdrawal, can inhibit the apoptosis of endometrial stromal cells by raising the Bcl-2/Bax proportion and blocking the expression of Caspase-3, resulting in blocking the process of menstrual-基金项目:国家自然科学基金(30901608);中央级公益性科研院所基本科研业务费专项资金(2009GJSSJKA02)收稿日期:2013-05-15 修回日期:2013-05-23*通讯作者:xiangboxuhappy@126.comlike changes in mouse.
2013 Vol. 21 (7): 441-444 [Abstract]（
47
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Guan Huangtao,Li Cuiling,Xiong Jinwen,Zhou Yuanzhong,Pang Xuebing,Reng Ning,Xiong Chengliang
To explore effects of intervention on contraceptive awareness, behavior and service utilization among high-income youth in Wuhan, in order to provide references for promoting appropriate technologies of contraception. Methods: Two hundred and thirty-eight high-income youth were recruited with typical sampling. Seminars, promotional materials, professional websites and other intervention measures were conducted, and the contraceptive awareness, behavior and service utilization six months after the intervention were evaluated. Results: Data of 226 respondents were analyzed after the intervention. The awareness rate of more efforts of oral contraceptives, emergency contraception, the interval between contraceptive discontinuance and pregnancy, emergency contraception for condom breakage in the ovulation phase were 10.91%, 12.30%, 55.32%, 12.56% before the intervention, and 22.31%, 26.30%, 71.19% and 22.42% after the intervention (P all <0.05). About 89.24% of the high-income youth thought seminars and publicity materials could meet the demand for the knowledge of contraception, 92.87% of them had viewed the professional website for the intervention, and 70.55% thought the professional website could provide the access to contraceptive services. Conclusion: Lack of awareness on contraception is found in high-income young people. Professional websites, publicity and education may significantly improve the awareness and service utilization on contraception among them.
2013 Vol. 21 (7): 445-448 [Abstract]（
56
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Ren Xiupeng,Zhang Li,Du Lirong,Zhang Yanming,Liu Xiaoqun,Li Guozheng
To explore the focus of family planning work on women with different marital status. Methods: According to marital status, 695 women seeking for induced abortion in two clinics were divided into 3 groups, as single group, unproductive group and multiparous group. A questionnaire including the personal information, knowledge of contraception and reproduction were answered by all female abortion patients and male partners of three groups. Results: The age of sexual debut and the age of initial abortion in the single group were less than other two groups, and the difference was significant (P<0.01). Total numbers of abortion and numbers of more than 2 times of abortion in 1 year in the multiparous group was more than other two groups (P<0.01). Women in the multiparous group knew most about contraception and side effects of abortion, but women in single group knew least (P<0.01). Male partners in the single group knew most contraceptive knowledge, while the multiparous group knew least. No contraception was the most common reason in this unwanted pregnancy of the three groups. Conclusion: According to different women with different marriage and fertility status, family planning services and reproductive health education should be different.
2013 Vol. 21 (7): 449-453 [Abstract]（
42
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Li Jianying
To explore clinical effects of GyneFix IN intrauterine device (IUD), MCu IUD, MLCu375 IUD and γ-IUD. Methods: Effects and side effects of four types of IUD using in 3000 reproductive women were evaluated by clinical comparison and three years' follow up. Results: One thousand and twenty women, 1000 women, 400 women and 400 women used GyneFix IN IUD, MCu IUD, MLCu375 IUD and γ-IUD, respectively. In three years, pregnancy rates with GyneFixIN IUD, MCu IUD, MLCu375 IUD and γ-IUD were 1.54/100 women year,4.49/100 women year,1.92/100 women year,3.53/100 women year, respectively (P<0.05). The expulsion rates were 4.07/100 women year, 5.36/100 women year, 4.80/100 women year, 5.62/100 women year, respectively(P<0.05). In the side effects, women who were using MCu IUD had the most obvious symptoms of aches and bleeding. Conclusion: The results suggest that the GyneFix IN IUD is worth of being spread for its good effect and less side effects.
2013 Vol. 21 (7): 454-457 [Abstract]（
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Zheng Tianjing
To explore the clinical effects and safety of being inserted intrauterine device (Mirena) for preventing recurrence after diagnostic dilation and curettage for endometrial polyps. Methods: The clinical and follow-up data of 120 women with endometrial polyps were retrospectively analyzed. The diagnostic dilation and curettage of endometrial polyp guided by ultrasound was conducted. Women were divided into two groups randomly, the treatment group for being inserted Mirena and the control group without intrauterine device. The therapeutic effects of intrauterine device on preventing recurrence of endometrial polyps in different groups were compared during 6, 12 and 24 months follow-up. Results: The operation was successfully completed for all the patients. The postoperative pathological result was the endometrial polyp. The hemoglobin level significantly increased after Mirena insertion in the treatment group. And when compared with the control group, the endometrial thickness was significantly thinner and recurrence rates were significantly lower at three follow-up visits in the treatment group (P all <0.05). No obvious adverse reaction was found. Conclusion: The insertion of intrauterine device (Mirena) after diagnostic dilation and curettage guided by ultrasound is an effective conservative therapy for endometrial polyps. It is suitable for primary health care institutions and family planning service stations where are lacking in hysteroscopy.
2013 Vol. 21 (7): 458-460 [Abstract]（
60
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Yuan Shuling
To explore the effect of Triquilar use after medical abortion. Methods: A total of 843 women with the gestational sac expulsion after medical abortion were divided into two group. One day after the gestational sac expulsion, Triquilar was taken in the study groups. The regular follow-ups were conducted in study and control groups. Results: The duration of vaginal bleeding were 13.24±4.41 days and 21.37±7.65 days, the rates of residue in the uterus were 10.49% and 40.42%, the endometrial repair was found in 86.34% of the study group and 15.24% of the control group, and the average time of menstrual restoration were 30.12±4.75 days and 38.14±9.78 days, showing significant differences. Conclusion: Triquilar can effectively shorten the duration of vaginal bleeding, reduce the intrauterine residue, promote the repair of endometrium, and restoration of the normal menstrual cycle.
2013 Vol. 21 (7): 461-462 [Abstract]（
54
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Liu yan,Guo Yixing
To explore the micro-column gel Coombs test and test tube Coombs test for IgG titre detection in serum of pregnant women with blood type O, and to establish the critical titre for IgG micro-column gel Coombs test. Methods: Blood samples of pregnant women with blood type O were detected simultaneously by the micro-column test and the tube test. Results: On average, two titers higher was found with the micro-column gel Coombs test than with the test tube Coombs test. No statistically significant difference in the positive rate was found between the two methods with 1:256 of micro-column gel reagent as the field value (P>0.05). The two methods had a high correlation (χ2=191.340,P<0.01,Kappa index: 0.542). Conclusion: The two detection reagents are in good consistency. The method of micro-column gel Coombs test is simpler, more standardized and its result is easier to judge, resulting in more worthy of clinical use. In addition, the clinical reference value suggested by this study should be not less than 1:256.
2013 Vol. 21 (7): 464-465 [Abstract]（
60
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Shi Wei,Xu Li,Liang Na,Yue Hengxue
To explore the contraceptive model of non-invasive insertion of intrauterine device (IUD) in rats. Methods: Fifty SD rat moms were assigned into non-invasive, invasive, non-invasive sham, invasive sham and blank control groups randomly. An copper-IUD was placed into the unilateral uterus through the vagina-cervix way in the non-invasive group and through the intraperitoneal-uterus way in the invasive group. The IUD was removed immediately after the operation mentioned above was conducted in the non-invasive sham and the invasive sham groups. The sixth day after modeling, the successful rate of insertion, the expulsion rate, uterine morphological changes and concentrations of TXB2 and 6-keto-PGF1α in the uterine flushing were evaluated.Results: The successful rates of insertion were all 100% in non-invasive, invasive and sham groups. The IUD expulsion rate of the noninvasive group was lower than that of the invasive group, while no significant difference was found (P>0.05). The peritoneal heterotopic was found in two rats. The extents of the uterine congestion and edema and the adhesion of abdominal organs in the non-invasive group were much less than those of the invasive group(P all <0.05). The concentrations of TXB2 in the non-invasive group and the invasive group were significantly lower than that of the blank control group, while the concentrations of 6-keto-PGF1α were much higher (P<0.01). Endometrial epithelial defects, inflammatory cell infiltrates and scattered thrombus were obvious in the non-invasive group and the invasive group, especially in the site of IUD insertion of the invasive group. Conclusion: It is feasible to simulate clinical IUD< insertion for contraception in the rat, and the rat model could be used for the study on side effects of IUD use And less damage on the endometrium with the non-invasine approach is suggested.
2013 Vol. 21 (7): 466-471 [Abstract]（
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