To investigate the effects of the ureteral stenting inserted for treating pregnant women with ureteral calculus during pregnancy on their microinflammation and pregnancy outcomes. Methods: The clinical data of 94 women with ureteral calculus during pregnancy who had hospitalized from December 2020 to December 2023 were selected. These women were divided into two groups according to the different treatment. The women in the study group had received ureteral stenting, while the women in the control group had received conservative treatment. The clinical efficacy, the inflammatory cytokines level before and after treatment, the pain degree and the incidence of the adverse pregnancy outcomes of the women were compared between two groups. Results: The effective rate (89.6%) of the women in the study group was significantly higher than that (65.2%) of the women in the control group. After 24 hours of treatment, the levels of the serum procalcitonin (0.06±0.03 ng/ml) and C-reactive protein (5.13±1.28 ng/L), and the white blood cell count (6.25±1.26×109/L) of the women in the study group were significantly lower than those (0.08±0.05 ng/ml, 8.12±2.35 ng/L) and （8.36±1.82×109/L) of the women in the control group. The visual analogue scale of the pain degree (2.14±0.42 points) and the incidence of the adverse pregnancy outcomes (2.1%) of the women in the study group were significantly lower than those (3.23±0.63 points and 17.4%) of the women in the control group (all P<0.05). Conclusion: The application of the ureteral stenting for treating the pregnant women with ureteral calculus during pregnancy has better effectiveness, and which can effectively attenuate the inflammation response, protect the renal function by relieving the obstruction and promote the recovery of the women, and with the better safety.