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| Values of the levels of serum calcium, phosphorus and D-dimer of pregnant women before delivery for predicting their uterine inertia-induced postpartum hemorrhage |
| Deyang Maternal and Child Health Care Hospital, Deyang, Sichuan Province, 618000 |
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Abstract To explore the values of the levels of serum calcium, phosphorus and D-dimer of pregnant women before delivery for predicting their uterine inertia-induced postpartum hemorrhage. Methods: 106 women who had delivered in hospital from October 2018 to October 2023 were collected in this study retrospectively. These women were divided in 21 cases with uterine inertia-induced postpartum hemorrhage in observation group and 85 cases without uterine inertia-induced postpartum hemorrhage in control group according to whether the uterine inertia-induced postpartum hemorrhage occurred or not. The medical records of the women in the two groups were collected. The levels of the prenatal serum calcium, phosphorus and D-dimer of the women were compared between the two groups. Multivariate Logistic regression analysis was used to screen the risk factors of the uterine inertia-induced postpartum hemorrhage of the women. The values of the levels of the prenatal serum calcium, phosphorus and D-dimer of the women for predicting their uterine inertia-induced postpartum hemorrhage was analyzed. Results: The levels of the prenatal serum calcium (2.39±0.31 mmol/L) and phosphorus (1.27±0.30 mmol/L) of the women in the observation group were significantly lower than those (2.66±0.28 mmol/L and 1.53±0.35 mmol/L) of the women in the control group. The prenatal serum D-dimer level (0.40±0.09 mg/L) of the women in the observation group was significantly higher than that (0.32±0.10 mg/L) of the women in the control group (all P<0.05). Logistic regression analysis showed that the low serum calcium and phosphorus levels, the high D-dimer level, the advanced age, the high body mass index value and the prolonged labor duration of the women were the risk factors of their uterine inertia-induced postpartum hemorrhage (P<0.05). The area under the curve (AUC), the sensitivity and the specificity of the combined levels of the serum calcium, phosphorus, and D-dimer of the women for predicting their uterine inertia-induced postpartum hemorrhage were 0.912, 95.2% and 50.6%, respectively, and the predictive efficacy of which was significantly higher than that of the serum calcium level, the phosphorus level or the D-dimer level alone (all P<0.05). Conclusion: The low levels of calcium and phosphorus, and the high D-dimer levels before delivery, the advanced age, the prolonged labor duration and the high body mass index value of the women are the risk factors of their uterine inertia-induced postpartum hemorrhage. The combined detection of the serum calcium, phosphorus, and D-dimer levels of the women can effectively predicting the occurrence of their uterine inertia-induced postpartum hemorrhage.
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