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| Analysis of the risk factors of the adverse pregnancy outcomes of super-aged multiparous women |
| The First Affiliated Hospital of medical school of Shantou University, Shantou, Guangdong Province, 515000 |
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Abstract To study the adverse pregnancy outcomes and the related risk factors of super-aged multiparous women in the east of Guangdong province. Methods: This was a prospective study that included 120 super-aged multiparous women diagnosed and treated in hospital from June 2020 to April 2022. These women were divided into group A (women with adverse pregnancy outcomes) and group B (women with normal pregnancy outcomes) according to their pregnancy outcomes. The clinical data of the women were compared between the two groups. Multivariate logistic regression was used to analyze the risk factors of the adverse pregnancy outcomes of the women. Results: The gestational weeks at delivery (39.0±1.0 weeks), the neonatal weight (3160.1±380.5g), the thyroid dysfunction rate (15.6%), the gestational diabetes mellitus rate (43.8%), the diabetes mellitus rate (23.4%) and the uterine fibroids rate (43.8%) of the women in group A were significantly different from those (37.7±1.8 weeks, 3040.9±591.1g, 3.6%, 25.0%, 7.1% and 23.2%) of the women in group B (all P<0.05). The correlation analysis showed that the gestational weeks at delivery, the neonatal weight, the thyroid dysfunction, the gestational diabetes mellitus, the diabetes mellitus and the uterine fibroids of the women were associated with their adverse pregnancy outcomes. Multivariate logistic regression analysis showed that the less gestational weeks at delivery, the higher neonatal weight, the thyroid dysfunction, the gestational diabetes mellitus, the diabetes mellitus and the uterine fibroids of the super-aged multiparous women were all the risk factors of their adverse pregnancy outcomes. Conclusion: In clinical practice, the risk factors of the super-aged multiparous women should be monitored in time to decrease the occurrence of their adverse pregnancy outcomes.
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