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| Risk factors of postpartum chronic kidney disease of women with hypertensive disorders complicating pregnancy |
| Shanxi Hospital of Traditional Chinese Medicine, Taiyuan, Shanxi Province, 030000 |
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Abstract To analyze the risk factors of postpartum chronic kidney disease (CKD) of women with hypertensive disorders complicating pregnancy (HDPs). Methods: The maternal case records of 3185 women who had been given antenatal examination in hospital from July 2017 to June 2021 were analyzed retrospectively, of which, 726 women with HDPs were included in observation group and 2459 women without HDPs were included in control group. The clinical data, such as pre-pregnancy conditions, past medical history, personal history, family history and pregnancy and birth history of the women in the two groups were collected. The clinical data of the women with postpartum CKD were compared between the two groups. The risk and the risk factors of CKD occurrence of the women with HDPs were analyzed. Results: The age, the pre-pregnancy body mass index, and the proportions of the first pregnancy, cesarean section and childbirth complications of the women in the observation group were significantly higher than those of the women in the control group. The incidence of CKD (5.0%) of the women in the observation group was significantly higher than that (1.4%) of the women in the control group (all P＜0.05). The risk of CKD of the women in the observation group was 5.54 times higher of that of the women in the control group (95%CI 3.43-10.65). After adjusting the confounding factors of the women with HDP, the age of the women at delivery≥35 years old was still a risk factor of their CKD occurrence (OR=2.31, 95%CI 1.30-3.89). The risk of CKD occurrence of the women with HDP who gave birth ≥2 times was significantly lower than that of the primiparas (OR=0.34, 95%CI 0.14-0.74) (all P＜0.05). Conclusion: The women with HDPs are in the high risk of developing CKD, particularly those women ≥35 years old, it is suggested that the renal function of the women with HDPs should be checked regularly after delivery, so as to intervene and treat in time.
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