|
|
|
| Efficacy of the blood flow resistance by ultrasound combined with the carbohydrate antigen for diagnosing endometrial cancer |
| First Affiliated Hospital of Anhui University of Technology(Huainan First People's Hospital), Huainan, Anhui Province, 232000 |
|
|
|
|
Abstract To analyze the efficacy of the blood flow resistance characteristics evaluated by ultrasound combined with the carbohydrate antigen detection of patients for diagnosing their endometrial cancer. Method: 35 women with endometrial cancer diagnosed and treated in hospital from January 2021 to June 2023 were selected in group A retrospectively, and 21 women with benign endometrial lesions were selected in group B. In addition, 56 healthy women who came to hospital for physical examination during the same period were included in group C. All the women in the three groups had undergone ultrasound examination to obtain the blood flow resistance related parameters values. The level of carbohydrate antigens(CA) the women in the three groups was detected. Multivariate logistic regression was used to analyze the risk factors of endometrial cancer occurrence. Receiver operating characteristic(ROC) curve was used to analyze the diagnostic efficacy of the blood flow resistance characteristics evaluated by ultrasound combined with the CA level of the women for their endometrial cancer. Results: The proportion of the coexistence of blood flow high and low resistance of the women in group A, group B, and group C had decreased gradually, and the serum levels of CA125, CA199, and CA153 of the women in group A, group B, and group C had also decreased gradually(all P<0.05). Multivariate logistic regression analysis showed that the low values of the blood flow resistance and the high levels of CA125, CA199 and CA153 of the women were the independent risk factors of their endometrial cancer occurrence(P<0.05). The area under the curve of the ultrasonic blood flow resistance parameters values and the levels of CA125, CA199 and CA153 of the women for diagnosing their endometrial carcinoma were 0.734, 0.711, 0.705, and 0.722, respectively. The area under the curve, the sensitivity, the specificity and the accuracy of the combined ultrasonic blood flow resistance parameters values and the CA levels of the women for diagnosing their endometrial carcinoma were 0.821, 87.5%, 78.6% and 83.0%, respectively, and which were significantly higher than those of the ultrasonic blood flow resistance parameters values or the CA levels. Conclusion: The accuracy of the combined ultrasonic blood flow resistance parameters values and the CA levels of the women for diagnosing their endometrial carcinoma is high, and which has certain clinical application value.
|
|
|
|
|
|
|
|
|
