|
|
|
| Diagnostic value of the serum anti Mullerian hormone and homocysteine levels of infertility women for their polycystic ovary syndrome and their correlation with the treatment outcomes for infertility |
| 1. Beijing Chuiyangliu Hospital, Beijing, 100021；2. Inner Mongolia Autonomous Region People's Hospital, Hohhot |
|
|
|
|
Abstract To analyze the diagnostic value of serum anti Mullerian hormone(AMH) and homocysteine(Hcy) levels of infertility women for their polycystic ovary syndrome(PCOS), and to study the correlation between the AMH and Hcy levels of the women and their infertility outcomes. Methods: The clinical data of 81 women with PCOS or with diminuted ovarian reserve(DOR) admitted to hospital from September 2021 to March 2022 were selected as the research objects, including 42 women with PCOS in group A and 39 women with DOR in group B. 40 healthy women were selected in group C during the same time. The serum levels of AMH and Hcy of the women were compared among the three groups. Logistics regression model was used to establish the diagnostic model for PCOS. Spearman correlation test was used to analyze the correlation between the AMH and Hcy levels of the women with PCOS and their outcomes after 1 year of treating their infertility. Results: The serum AMH and Hcy levels of the women were significantly different among the three groups, and which of the women in group A were the highest(P<0.05). The diagnostic model of PCOS constructed by logistics regression model was Log(P)=0.675×AMH+0.701×Hcy+0.644(P<0.05). The area under the curve(AUC) of the combined AMH and Hcy levels of the women for diagnosing their PCOS was 0.970, which was significantly higher than that(0.850) of the AMH level or that(0.895) of the Hcy level alone(P<0.05). In group A, the women were followed up for 1 year, the levels of serum AMH(12.03±1.21 ng/ml) and Hcy(11.79±1.31μmol/L) of the women with pregnancy were significantly lower than those(15.12±2.31 ng/ml and 14.11±1.89μmol/L) of the women without pregnancy, and the levels of serum AMH and Hcy of the infertility women with PCOS were positively correlated with their pregnancy outcomes(all P<0.05). Conclusion: The combined AMH and Hcy levels of the women for diagnosing their PCOS has effect, and both the serum AMH level and Hcy level of the infertility women with PCOS are positively correlated with their pregnancy outcomes.
|
|
|
|
|
|
|
|
|
