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| Observation of the clinical efficacy of antiseptic decoction combined with human interferon α2b gel for treating patients with cervical high-risk human papillomavirus infection |
| 1.The second Clinical College of Zhejiang Chinese Medicinal University, Hangzhou, Zhejiang Province, 310053; 2.Wenzhou Integrated Traditional Chinese and Western Medicine Hospital, Wenzhou, Zhejiang Province; 3.Dalian Medical University, Dalian, Liaoning Province |
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Abstract To observe the clinical efficacy of antiseptic decoction combined with human interferon α2b gel for treating patients with cervical high-risk human papillomavirus (HR-HPV) infection. Methods: 90 patients with HR-HPV infection who met the inclusion criteria from December 2020 to December 2022 were randomly divided into 30 cases without treatment in group A, 30 cases with treatment of antiseptic decoction in group B for 3 menstrual cycles continually and 30 cases with treatment of antiseptic decoction combined with human interferon α2b gel in group C for 3 menstrual cycles continually. The blank group was not given medicine, the western medicine group was treated with human interferon α2b gel alone, and the combined group was treated with human interferon α2b gel combined with antiseptic mixture. All three groups were treated. The curative effect and the changes of TCM syndrome scores of the patients in the three groups after treatment were observed. Results: The TCM syndrome scores of the patients in the three groups after treatment had decreased significantly (P<0.05). The improvement of TCM syndrome score of the patients in group C was significantly better than that of the patients in group B and in group A (P<0.05). The clinical efficacy and the TCM changes of the patients of the patients after treatment had significant differences among the three groups (P<0.05), and which of the patients in group C were significantly better than those of the patients in group B and in group A (P<0.05). Conclusion: The antiseptic decoction combined with human interferon α2b gel for treating the patients with cervical HR-HPV infection can effectively relieve their clinical symptoms and increase their negative conversion rate of HR-HPV.
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