|
|
|
| Influence of different anesthetic drugs used in gynecological laparoscopic surgery on intraoperative hemodynamics and indexes, and prognosis |
| 1. The Eighth People's Hospital, Hefei, Anhui Province, 238000；2. Chaohu Hospital, Anhui Medical University |
|
|
|
|
Abstract To analyze the influence value of the different anesthetic drugs used in gynecological laparoscopic surgery of patients on their intraoperative hemodynamics and indexes, and their prognosis. Methods: The clinical data of 78 patients who had undergone laparoscopic ovarian cyst excision from January 2018 to December 2022 were analyzed retrospectively. According to the intraoperative anesthetic drugs used, these patients were divided into 40 patients with remifentanil for anesthetic in group A and 38 patients with fentanyl citrate for anesthetic in group B. The value changes of heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), the anesthetic maintenance time, the awakening time, the extubation time, and the initial analgesia time of the patients in the two groups before anesthesia (T0), after induction (T1), during intubation (T2), at skin resection (T3), and at extubation (T4) were observed. The alertness/sedation observation (OAA/S) score and the pain score by visual analogue scale (VAS) were used to evaluate the postoperative consciousness and pain degree of the patients. Kaplan-Meier survival curve was drawn to observe the occurrence of the adverse reactions of the patients in the two groups within 48h after analgesia. The anesthesia satisfaction of the patients in the two groups was investigated by the self-designed satisfaction scale. Results: The observations for the patients at different time points during operation showed that the stability of the HR, SBP, and DBP values of the patients in group A were significantly better than those of the patients in group B. The duration of anesthesia (97.59±15.05min) of the patients in group A was significantly longer than that (85.36±8.27min) of the patients in group B. The awakening time (5.40±0.87min), the extubation time (6.51±0.86min), and the first pain duration (10.50±0.87min) of the patients in group A were significantly shorter than those (13.09±1.81min, 18.67±1.62min, and 53.68±7.84min) of the patients in group B. The OAA/S score (2.88±0.76 points) of the patients in group A at postoperative awaking was significantly higher than that (1.92±0.85 points) of the patients in group B (P＜0.05), but there was no significant difference in the VAS score of the patients at 48h after surgery between the two groups. The total occurrence of postoperative adverse reactions (5.0%) of the patients in group A was significantly lower than that (26.3%) of the patients in group B, and the rate of anesthesic satisfaction (77.5%) of the patients in group A was significantly higher than that (52.6%) of the patients in group B (all P＜0.05). Conclusion: Compared with those of remifentanil, fentanyl citrate can maintain the hemodynamic stability of the patients under anesthesia. The postoperative recovery time of the patients with remifentanil for anesthesia is significantly better than that of fentanyl citrate, and the analgesic time is significantly shorter, so it is necessary to pay attention to the analgesic needs after surgery of the patients with remifentanil for anesthesia.
|
|
|
|
|
|
|
|
|
