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Abstract To study the clinical characteristics of women with asymptomatic bacteriuria (ASB) during pregnancy. Methods: The clinical data of 65 women with ASB during pregnancy who had registered, examined, and delivered in Beijing Obstetrics and Gynecology Hospital in the past 10 years (in study group), and 150 women without ASB during the same period (in control group) were analyzed retrospectively. The general condition, the pregnant complications situations, and the neonatal outcomes of women were compared between the two groups. The etiological characteristics of the women with ASB were analyzed. Results: The proportion of primipara (61.5%) in the study group was significantly lower than that (84%) in the control group. The gestational weeks (36.5±5.7 weeks) of the women at delivery in the study group was significantly shorter than that (38.5±2.2 weeks) of the women in the control group. The incidence of low birth weight (10.8%) of the infants in the study group was significantly higher than that (2.0%) of the infants in the control group. The incidences of the preterm birth, the fetal growth restriction, and the pregnancy-induced hypertension of the women in the study group were 23.1%, 26.2%, and 29.2%, respectively, and which were significantly higher than those (6.7%, 5.3%, and 4.7%, respectively) of the women in the control group (P<0.05). The granulocyte to lymphocyte number ratio (NLR) of the women during the third trimester of pregnancy or at the onset of ASB in the two groups were 3.27±1.33 and 5.14±0.96, which were all significantly higher than those (4.47±1.82 and 3.84±1.41) of the women during the first trimester of pregnancy (P<0.05), but which of the women had no significant difference between the two groups. There were no significant differences in the maternal age, the number of pregnancies, the incidence of premature rupture of membranes, and the neonatal Apgar score of the women between the two groups. Escherichia coli was the main pathogenic bacteria of the women with ASB, and which was resistant to a variety of antibiotics, including piperacillin sulbactam, ceftriaxone, cefuroxime, and ceftazidime. Conclusion: There is a correlation between ASB of the pregnant women and their adverse pregnancy outcomes. The main pathogenic bacteria of the women with ASB are gram negative bacillus, with mainly escherichia coli.
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