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| Effects of epidural anesthesia with different doses of dexmedetomidine during cesarean section of women on their hemodynamics and incidence of chills |
| Hefei Second People's Hospital(Hefei Hospital Affiliated to Anhui Medical University), Hefei, Anhui Province, 230011 |
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Abstract To explore the effects of epidural anesthesia with different doses of dexmedetomidine during cesarean section of women on their hemodynamics and incidence rate of chills. Methods: 112 pregnant women who wanted cesarean section were selected and were randomly divided into group A(37 cases), group B(37 cases), and group C(38 cases) between January 2019 and June 2022. Dexmedetomidine of 0.2μg/kg, dexmedetomidine of 0.5μg/kg, and dexmedetomidine of 0.8μg/kg were given the women in group A, in group B, and in group C during cesarean section, respectively. The values of hemodynamics indexes, such as systolic blood pressure(SBP) and heart rate(HR), before anesthesia(T1), after 5 min of administration(T2), at skin incision(T3), and at the end of surgery(T4), the analgesic effect and recovery quality, such as complete block time and Steward recovery score, the degree of chills during peri-anesthesia period and occurrence of adverse reactions, and the values of postpartum levator hiatus and pelvic floor indexes, such as levator hiatus diameter(LHD) and levator urethral gap(LUG) of the women were compared among the three groups. Results: The change amplitude of the SBP and HR values, and the LHD and LUG levels of the women in group A were significantly higher than those of the women in group B and those of the women in group C, the incidence of chills during anesthesia(35.1%) of the women in group A was significantly higher than that(13.5%) of the women in group B and that(13.2%) of the women in group C. The Steward recovery score(3.61±1.02 points) of the women in group A was significantly lower than that(4.37±1.28 points) of the women in group B and that(4.51±1.37 points) of the women in group C, but which of the women in group B had no significantly different from those of the women in group C. The total occurrence of adverse reactions of the women in group A(8.1%) or in group B(10.8%) was significantly lower than that(34.2%) of the women in group C(all P＜0.05). Conclusion: Dexmedetomidine of 0.5μg/kg·h used in cesarean section under epidural anesthesia of the women can stabilize their intraoperative hemodynamics, and which has good analgesic effect, can reduce the risk of chills and adverse reactions, can ensure the maternal recovery quality, and can improve the postpartum levator hiatus and pelvic floor condition.
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