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| Prediction of three-dimensional power Doppler ultrasound combined with color Doppler for fetal growth restriction of pregnant women during the first trimester of pregnancy |
| Baoji Maternal and Child Health Care Hospital, Shaanxi Province, 721000 |
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Abstract To investigate the predictive effect of three-dimensional power Doppler ultrasound combined with color Doppler for fetal growth restriction (FGR) of pregnant women during the first trimester of pregnancy. Methods: The clinical data of 317 pregnant women who underwent fetal nuchal translucency thickness (NT) examination by ultrasound during the first trimester of pregnancy from October 2020 to May 2021 were collected retrospectively. These women were divided into group A (298 cases without FGR) and group B (19 cases with FGR) according to the follow-up results after delivery. The general clinical data of the women were compared between the two groups. And the values of fetal crown-rump length (CRL), placental volume (PV), placental flow index (FI), vascularization index (VI), and vascularization flow index (VFI) were compared between the two groups, and the predictive efficacy of which for FGR was analyzed. Results: There were no significant differences in the FI value and Apgar scores at 1min and 5min after birth of the fetuses between the two groups (P＞0.05), but there were significant differences in the values of body weight, CRL, PV, VI, and VFI of the fetuses between the two groups (all P＜0.05). Multifactor logistics regression analysis showed that the reductions of the values of CRL, PV, VI, and VFI of the fetuses was the independent risk factors for the FGR occurrence (P＜0.05). Receiver operating characteristic (ROC) curve analysis showed that the CRL value, the PV value, the VI value, and the VFI value of the fetuses alone for diagnosing the FGR were valuable. The combination of the values of CRL, PV, VI, and VFI of the fetuses for diagnosing the FGR was also valuable, the area under the curve (AUC) of which was 0.762, with the highest AUC, and the sensitivity of which was 84.2%. Conclusion: The efficacy of three-dimensional power Doppler ultrasound combined with color Doppler for predicting FGR of the pregnant women during the first trimester of pregnancy is high, which is helpful for early diagnosis and timely intervention measures for FGR.
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