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Effects of laparoscopic salpingectomy for treating women with fallopian ectopic pregnancy on their serum sex hormones and anti-Mullerian hormone levels |
Qingbaijiang District People's Hospital, Chengdu, Sichuan Province, 610300 |
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Abstract To study the effects of laparoscopic salpingectomy for treating women with emergency fallopian ectopic pregnancy on the levels of the serum sex hormones and anti-Mullerian hormone (AMH). Methods: 95 women with ectopic pregnancy who were admitted to emergency outpatient department of the hospital between January 2019 and January 2021 were collected as the research subjects, and these women were divided into two groups according to different surgical methods. Among these women, 49 cases were treated with laparoscopic salpingectomy in group A, and 46 cases underwent fallopian fenestration were in group B. The perioperative status, the levels of serum sex hormones and AMH, and the situation of postoperative follow-up of the women were compared between the two groups. Results: There were no significant differences in the pregnancy site, pelvic adhesion, contralateral fallopian tube abnormality, intraoperative blood loss, operation time, and hospital stay of the women between the two groups (P>0.05). There was no significant difference in the serum sex hormone level of the women before surgery and in the 6th month after surgery between the two groups. The serum follicle stimulating hormone level (7.46±1.42 mIU/ml)and estradiol (57.98±10.16 pg/ml)level of the women in group A in the 3rd month after surgery were significantly higher than those (6.74±1.78 mIU/ml and 40.15±11.04 pg/ml)of the women in group B. The recurrence of ectopic pregnancy of the women in group A within 1 year of follow up after surgery was 4.1%, which was significantly lower than that (17.4%)of the women in group B (all P<0.05). There was no significant difference in the rate of intrauterine pregnancy of the women within 1 year after surgery between the two groups. Conclusion: Compared with those of fallopian fenestration, laparoscopic salpingectomy for treating women with ectopic pregnancy has the same surgical effect, with lower recurrent ectopic pregnancy rate after surgery, however, which affects the FSH, E2, and AMH levels of the women in the near future after surgery. So it is necessary to select the operative methods for the women with ectopic pregnancy according to their actual situation in clinical treatment.
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