To explore the value of transvaginal three-dimensional ultrasound (3D-TVS) for evaluating the endometrium situation of infertility patients with intrauterine adhesions (IUA), and to study the correlation between the endometrium situation of the infertility patients and their pregnancy outcomes after in vitro fertilization embryo transfer (IVF-ET). Methods: The clinical data and the ultrasonic imaging data of 98 infertile patients with IUA who had accepted IVF-ET were analyzed retrospectively. All the patients had undergone hysteroscopic transvaginal resolution of adhesions (TCRA) and had received IVF-ET within 1 year after operation. According to the pregnancy outcomes, these patients were divided into group A (55 cases with clinical pregnancy) and group B (43 cases without pregnancy). The endometrial thickness and type, and the ultrasonogram by 3D-TVS during the implantation window of the patients in the two groups were analyzed. Results: There were no significant differences in the endometrial thickness ［(8.40±1.33mm (5.8-11.5mm) vs. (7.83±1.69mm (4.8-11.7mm)］ and the endometrial type of the patients between the two groups (all P＞0.05). There was significant difference in the proportion of the normal sonogram by 3D-TVS 3D (3.6% vs. 20.9%) of the patients between the two groups (P＜0.05). The abnormal sonogram by 3D-TVS 3D of the patients in group B were mainly manifested as endometrial limitation dark area and endometrial local defect area. Conclusion: D-TVS can accurately evaluate the abnormal echo changes of uterine cavity and endometrium of the infertility patients with IUA, which can provide important information for IVF-ET and the prognosis of infertility patients with IUA.