|
|
|
| Vaginal estrogen delivery system in Genitourinary syndrome of menopause |
| 1.NHC Key Laboratory of Reproductive Health Engineering Technology Research, Beijing, 100081; 2.Graduate School of Peking Union Medical College |
|
|
|
|
Abstract Genitourinary syndrome of menopause (GSM) is a highly prevalent perimenopausal symptom that progressively worsens over time but it is currently not appropriately treated in a timely manner due to lack of awareness and attention by patients and their physicians. Current therapies for this localized symptom include Menopause Hormone Therapy (MHT) and non-hormonal approaches, with MHT for local vaginal delivery of estrogen being the current first-line treatment option for GSM due to its reliable safety and efficacy. The main topical estrogen Drug Delivery System (DDS) for GSM in recent years include tablets, capsules, suppositories, creams, vaginal rings (IVRs) and gels. This article reviews the relevant marketed drugs and the progress of their development in recent years to provide some reference in clinical.
|
|
|
|
|
|
|
|
|
