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Abstract To explore the application efficacy of target-oriented control block plane of anesthesia during cesarean section. Methods: From January 2021 to December 2021, 98 pregnant women who wanted cesarean section were selected and were randomly divided into observation group and control group (49 cases in each group). The women in the observation group received 0.67% ropivacaine, and the puncture interval was L3-4, while the women in the control group received 0.5% bupivacaine, and the puncture interval was L2-3. The block plane, the block time of motor and sensory, the indexes of hemodynamics and stress, and the occurrence of hypotension at the time of skin incision and the fetal delivery of the women in the two groups were observed. Results: There were no significant difference in the preoperative hemodynamic indexes levels of the women between the two groups (P>0.05). The mean arterial pressure and heart rate of the women in the observation group at 5min and 10min after administration were significantly better than those of the women in the control group (P<0.05). There were no significant differences in the levels of cortisol (Cor), endothelin (ET), superoxide dismutase (SOD), and malondialdehyde (MDA) levels of the women in the observation group among before anesthesia, immediately after anesthesia, and 1h after anesthesia (P>0.05). The levels of Cor, ET, and SOD of the women in the control group immediately after anesthesia were significantly higher than those before anesthesia and 1h after anesthesia, but the MDA level immediately after anesthesia was significantly lower than that before and 1h after anesthesia (P<0.05). Compared with those of the women in the observation group at the time of skin dissection and fetal delivery, more women in the control group had more than T8 and T6 block planes, and additional anesthetic drugs were needed (P<0.05). There was no significant difference in the onset time of sensory block of the women between the two groups (P>0.05). The maintenance time of motor block or sensory block of the women in the observation group was significantly shorter than that of the women in control group, and the onset time of motor block of the women in the observation group was significantly longer (P<0.05). The incidence of intraoperative hypotension (10.2%) of the women in the observation group was significantly lower than that (24.5%) of the women in the control group (P<0.05). Conclusion: During the cesarean section anesthesia of the women, the use of 0.67% ropivacaine is suitable for goal-directed control of the block plane, which can reduce the incidence of hypotension of these women with more stable hemodynamics.
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