|
|
|
| Anesthesia quality of patient under total intravenous anesthesia or static inhalation combined with intravenous anesthesia for laparoscopic hysterectomy and its effects on the stress response of these patient |
| Affiliated Hospital of Qinghai University, Xining, Qinghai Province, 810001 |
|
|
|
|
Abstract To analyze that anesthesia quality of patient under total intravenous anesthesia or static inhalation combined with intravenous anesthesia for laparoscopic hysterectomy, and to study its effects on the stress response of these patients. Methods: A total of 90 patients who wanted elective laparoscopic hysterectomy were selected and were randomly divided into group A(45 patients given total intravenous anesthesia)and group B(45 patients given the combined intravenous and inhalation anesthesia)according to the random number table from February 2018 to February 2021. The values of heart rate(HR), mean arterial pressure(MAP), central venous pressure(CVP), and oxygen saturation(SpO2)of the patients in the two groups before anesthesia(T0), during pneumoperitoneum(T1), during operation(T2), and after operation(T3)were observed. Ramsay sedation score was used to evaluate the anesthesia and sedative effect of the patients at T0 and T3. The levels of serum cortisol(Cor), norepinephrine(NE), and angiotensin II(AngⅡ II)of the patients at T0, T2, and in 1h after surgery(T4)of the patients were compared between the two groups. Results: There was no significant difference in the hemodynamic parameters of the patients at T0 between the two groups(P＞0.05). The values of HR, MAP, and CVP of the patients in group B at T1, T2, and T3 were significantly lower than those of the patients in group A(P＜0.05), there was no significant difference in the SpO2 value of the patients at T1, T2, and T3 between the two groups(P＞0.05). The values of HR, MAP, and CVP at different time of the patients in group A fluctuated greatly, and the CVP value of at different time of the patients in group B fluctuated greatly(P＜0.05). There was no significant difference in Ramsay scores of anesthesia and sedation of the patients at T0 and T4 between the two groups. There was no significant difference in the serum Cor, NE, and AngⅡ levels of the patients at T0 between the two groups(all P＞0.05). The levels of serum Cor, NE, and AngⅡ of the patients in group B were significantly lower than those of the patients in group A(P＜0.05). There was no significant difference in the incidence of adverse reactions(11.1% vs. 13.3%)of the patients between the two groups(P＞0.05). Conclusion: The total intravenous anesthesia or intravenous combined with static inhalation combined anesthesia during laparoscopic hysterectomy has good anesthesia quality and safety. Intravenous combined with static inhalation combined anesthesia has less impact on the hemodynamics and stress response indicators of the patients, which is conducive to maintaining their stable vital signs and reducing their stress response.
|
|
|
|
|
|
|
|
|
