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| Efficacy of transvaginal color Doppler ultrasound combined with serum cancer antigen 125 level for differential diagnosing benign or malignant ovarian tumors |
| 1.Rong County People's Hospital of Sichuan Province, Sichuan Province, 643100 |
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Abstract To analyze the values of peak systolic blood flow velocity (PSV) and resistance index (RI) measured by transvaginal color Doppler ultrasound combined with serum cancer antigen 125 (CA125) level for differential diagnosing benign or malignant ovarian tumors. Methods: A total of 91 patients with ovarian tumors from December 2017 to December 2021 were collected retrospectively. These patients were divided into group A (56 patients with benign ovarian tumors) and group B (35 patients with malignant ovarian tumors) according to their pathological results after surgery. The values of PSV and RI, and the CA125 level of the patients were compared between the two groups. The diagnostic value of the values of PSV and RI, and the CA125 level of the patients for their benign or malignant ovarian tumors was analyzed by receiver operating characteristic (ROC) curve. Results: The PSV value and the CA125 level of the patients in group B were significantly higher than those of the patients in group A, and the RI value of the patients in group B was significantly lower (all P＜0.05). ROC curve analysis showed that the specificity of the RI value for differential diagnosing benign or malignant ovarian tumors was the highest (88.2%). The sensitivity (83.0%), the accuracy (84.6%), and the negative predictive value (91.1%) of the PSV and RI values combined with the CA125 level of the patients for differential diagnosing their benign or malignant ovarian tumors were significantly higher than those of the PSV value, the RI value, or the CA125 level alone. Conclusion: The PSV value, the RI value, and the CA125 level of the patients with benign or malignant ovarian tumors are different. The PSV and RI values combined with the CA125 level of the patients for differential diagnosing their benign or malignant ovarian can improve the sensitivity and the accuracy of diagnosis, which is conducive to the development of subsequent treatment plan.
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